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There is probably no simple answer to this. Information can be found in the World Health Organisation document on desalination https://www.who.int/water_sanitation_health/publications/2011/desalination_guidance_en.pdf and some of the references that it gives.

The definitive guidelines on drinking water quality are the WHO (2011) Guidelines for drinking-water quality, 4th ed. Geneva, World Health Organization but you would have to determine what elements are of concern from your source water, process and any re-mixing with non-desalinated water.

Osteoporosis is mentioned in the following link; https://www.wcponline.com/pdf/Cotruvo.pdf

You can look up details of any chemical element of concern at; https://www.who.int/water_sanitation_health/dwq/chemicals/en/